Active Surveillance in Urologic Cancer: When Doing Less Is the Right Decision

This article forms part of Dr Deanne Soares’ urologic cancer education series, providing evidence-based guidance on treatment, recovery and life after urological cancer surgery.

For many people, a cancer diagnosis creates an immediate expectation that treatment must follow quickly — and that decisive action is always better than waiting.

In urologic cancer care, that assumption is not always correct.

For selected patients, active surveillance is not avoidance, denial or delay. In carefully chosen situations, it allows time to observe cancer behaviour without compromising the opportunity for effective treatment if it becomes necessary.

This article explains what active surveillance means in urologic cancer, when it is recommended, and how decisions are made between surveillance and intervention.

Patient summary

Key points to know:

  • Active surveillance is structured monitoring, not “doing nothing”

  • It is appropriate for selected low-risk cancers

  • Treatment remains an option if the cancer changes

  • Surveillance aims to preserve quality of life

  • Decisions are individualised and revisited over time

What is active surveillance?

Active surveillance involves regular, planned monitoring of a known cancer rather than immediate treatment.

Depending on the cancer type, surveillance may include:

  • blood tests (such as PSA)

  • imaging

  • biopsies at defined intervals

  • clinical review

The goal is to detect meaningful change, not to ignore disease.

Active surveillance is different from watchful waiting, which is typically used when treatment would not be offered even if progression occurred. Surveillance assumes treatment is available and will be used if indicated.

Why surveillance exists in modern cancer care

Not all cancers behave the same way.

Some urologic cancers:

  • grow very slowly

  • may never cause symptoms

  • may never threaten life expectancy

For these cancers, immediate treatment can expose patients to side effects without clear benefit.

Surveillance recognises that:

  • overtreatment causes harm

  • quality of life matters

  • timing of treatment can influence outcomes

This approach has evolved alongside better imaging, improved pathology and long-term outcome data.

Where active surveillance is commonly used

Prostate cancer

Active surveillance is most established in low-risk prostate cancer and selected favourable intermediate-risk cases.

It may be appropriate when:

  • cancer is low grade

  • disease volume is limited

  • imaging does not suggest aggressive features

  • PSA behaviour is stable

  • the patient is comfortable with close monitoring

For many men and people with prostates, surveillance allows years — and sometimes lifelong — avoidance of surgery or radiation.

Kidney cancer

Small renal masses are increasingly detected incidentally.

Active surveillance may be considered when:

  • tumours are small

  • imaging suggests indolent behaviour

  • growth rates are slow

  • surgery carries higher risk due to comorbidities

Surveillance in kidney cancer focuses on tumour behaviour over time, with surgery offered if growth or features change.

Bladder cancer (selected contexts)

Surveillance is also part of bladder cancer management in specific low-risk, non-muscle-invasive cases, where recurrence patterns are predictable and monitored closely.

It is important to address common misconceptions.

Active surveillance is not:

  • denial of cancer

  • lack of follow-up

  • avoiding difficult decisions

  • appropriate for high-risk disease

Surveillance is structured, intentional and requires commitment from both patient and clinician.

How decisions about surveillance are made

Choosing surveillance depends on three overlapping domains:

1. Cancer characteristics

  • grade and stage

  • imaging features

  • growth patterns

  • pathological markers

2. Patient factors

  • age and overall health

  • other medical conditions

  • baseline function

  • personal priorities and tolerance of uncertainty

3. System capability

  • access to regular monitoring

  • reliable follow-up

  • clear triggers for intervention

  • All three must align for surveillance to be safe.

The psychological side of surveillance

One of the most underestimated aspects of active surveillance is the mental load.

Some patients find reassurance in avoiding treatment side effects. Others worry that waiting means losing control, which is why surveillance works best when the plan, review points and triggers for action are clearly defined from the outset.

Neither reaction is wrong.

Successful surveillance includes:

  • clear education

  • predictable follow-up schedules

  • honest discussion about risk

  • permission to reconsider

Choosing surveillance does not lock patients into that decision indefinitely.

When surveillance stops being the right choice

Surveillance is not static.

Treatment may be recommended if:

  • cancer grade changes

  • growth accelerates

  • imaging becomes concerning

  • symptoms develop

  • patient priorities shift

Transitioning from surveillance to treatment is not a failure. It reflects a decision being updated in response to new information — which is exactly how surveillance is intended to function.

Surgical judgement and experience

In practice, active surveillance works best when offered by clinicians experienced in both operative and non-operative cancer management, who are comfortable recommending restraint when appropriate and intervention when necessary.

For patients: questions worth asking

If surveillance is discussed, helpful questions include:

  • What specifically are we monitoring?

  • How often will tests occur?

  • What would trigger treatment?

  • What are the risks of waiting in my case?

  • Can I change my mind later?

Clear answers reduce anxiety and improve confidence.

For GPs and referring clinicians

GPs play a crucial role in supporting patients on surveillance by:

  • reinforcing that surveillance is active care

  • helping manage test-related anxiety

  • monitoring general health and comorbidities

  • facilitating timely re-referral if concerns arise

Consistent messaging across care teams prevents unnecessary distress.

A note on individual decision-making

This information is intended to provide general guidance on active surveillance in urologic cancer, but it cannot replace an individual consultation. Decisions about surveillance depend on cancer characteristics, monitoring capability and patient priorities, and are best made through discussion with the treating team.

Conclusion

Active surveillance reflects a shift in modern cancer care — away from reflexive treatment and toward thoughtful, individualised decision-making.

For selected patients, doing less initially does not mean caring less — it means choosing treatment timing carefully, rather than reflexively.

Good cancer care is not defined by how quickly treatment is delivered, but by how appropriately it is chosen.

About the author:

Dr Deanne Soares is a Melbourne-based urologist with a subspecialist focus in robotic prostate, kidney and bladder cancer surgery.

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